NAD+ (500mg)

Description

What is NAD+ (Nicotinamide Adenine Dinucleotide)?

NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme found in all living cells, extensively studied for its role in cellular energy production, DNA repair, oxidative stress response, and metabolic regulation. As a central molecule in redox reactions, NAD+ facilitates the conversion of nutrients into energy and is a key regulator of mitochondrial function and gene expression pathways.

In preclinical and laboratory models, NAD+ has been examined for its potential to support healthy aging, enhance sirtuin activity, and influence processes related to inflammation, brain health, and genomic stability. Due to its foundational role in metabolism and cellular signaling, NAD+ continues to be a focus in anti-aging, neuroprotective, and metabolic disease research environments.

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NAD+ Product Specifications

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Why Choose BioEdge Research Labs NAD+?

• High Research-Grade Purity: Verified at >99% via third-party HPLC analysis

• Bulk 500 mg Format: Ideal for metabolic, cellular, and molecular research applications

• Secure Lab Packaging: Tamper-evident and light-resistant to protect compound stability

• Fast Shipping: Most orders ship within 24 hours after payment confirmation from our U.S.-based facility.

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Summary of Preclinical Research Findings

Anti-Aging and Longevity

• Studied for supporting sirtuin enzyme activation and epigenetic regulation

• Associated with improved cellular function in aging-related models

• Explored for effects on mitochondrial decline and energy balance with age

Energy Metabolism and Mitochondrial Function

• Investigated for its role in ATP production and redox homeostasis

• Studied in models involving mitochondrial repair and bioenergetics

• Linked to enhanced nutrient processing and inter-organelle signaling

Inflammation and Brain Health

• Used in preclinical models of neurodegeneration and cognitive decline

• Explored for modulation of inflammatory responses and immune signaling

• Associated with oxidative stress reduction and neuron protection

DNA Repair and Genomic Stability

• Studied for activation of PARP enzymes and repair of DNA strand breaks

• Evaluated for roles in chromatin remodeling and genomic maintenance

• Applied in cellular aging models for long-term genome support

Note: All findings described above are derived from non-human, preclinical laboratory research. No claims are made regarding safety or efficacy in humans or animals.

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Suggested Areas of Research

• Aging and sirtuin pathway activation studies

• Mitochondrial energy and ATP metabolism research

• Neurodegenerative and brain health models

• Oxidative stress and inflammation control pathways

• DNA damage response and genomic stability assays

• In vitro metabolic and longevity-related investigations

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Handling & Storage Guidelines

• Store NAD+ lyophilized powder at room temperature away from direct light

• After reconstitution, refrigerate immediately 

• Use only sterile, laboratory-grade solvents for preparation

• Avoid exposure to heat, moisture, or air to preserve stability

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For Research Use Only

NAD+ from BioEdge Research Labs is supplied exclusively for in vitro laboratory and scientific research.

• Not for human or animal use

• Not for therapeutic, diagnostic, or clinical application

• Purchase confirms that the buyer is a qualified researcher age 18 or older

• All use must comply with local laws and institutional safety protocols

Disclaimer: This content is for scientific and educational reference only. No therapeutic or health claims are made or implied.

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Summary of References

NAD+ in Anti-Aging and Longevity Research

• Gomes, A. P., et al. (2013). Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell, 155(7), 1624–1638. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076149/

• Imai, S., & Guarente, L. (2014). NAD+ and sirtuins in aging and disease. Trends in Cell Biology, 24(8), 464–471. https://www.ncbi.nlm.nih.gov/pubmed/24786309

• Yoshino, J., et al. (2018). NAD+ intermediates: The biology and therapeutic potential of NMN and NR. Cell Metabolism, 27(3), 529–547. https://www.ncbi.nlm.nih.gov/pubmed/31065944

NAD+ and Mitochondrial Energy Metabolism

• Canto, C., et al. (2015). NAD+ metabolism and the control of energy homeostasis: A balancing act between mitochondria and the nucleus. Cell Metabolism, 22(1), 31–53. https://www.ncbi.nlm.nih.gov/pubmed/26215259

• Verdin, E. (2015). NAD+ in aging, metabolism, and neurodegeneration. Science, 350(6265), 1208–1213. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469033/figure/F2/

• Rajman, L., et al. (2018). Therapeutic potential of NAD+ precursors in health and disease. Nature Reviews Drug Discovery, 17(7), 421–439. https://www.semanticscholar.org/paper/278fa4262ee3662ad4133dc249252ec1f41f42b8

NAD+ in Inflammation, Brain Health, and Cellular Protection

• Lautrup, S., et al. (2020). NAD+ in brain aging and neurodegenerative disorders. Cell Metabolism, 30(4), 630–655. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772416/

• McReynolds, M. R., et al. (2022). NAD+ analogs inhibit PARP enzymes and suppress inflammation. Cell Chemical Biology, 29(8), 1130–1142. https://pubmed.ncbi.nlm.nih.gov/35292961/

NAD+ in DNA Repair, Genomic Stability, and Cell Health

• Covarrubias, A. J., et al. (2022). NAD+ metabolism and its roles in cellular processes related to aging and DNA repair. Nature Reviews Molecular Cell Biology, 23(7), 499–519. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311062/

• Katsyuba, E., et al. (2020). NAD+ homeostasis in health and disease. Nature Metabolism, 2(1), 9–31. https://pubmed.ncbi.nlm.nih.gov/33384409/

 

BioEdge Research Labs
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At BioEdge, we are committed to providing research professionals with the highest quality peptides on the market. Every compound we supply is manufactured in a cGMP-certified facility, undergoes rigorous third-party testing, and is intended strictly for in vitro or laboratory research use only.