GHK – CU

Description

GHK-Cu

Lyophilized Powder | Third-Party Tested | USA-Manufactured

In Stock | Free Shipping on Orders Over $150

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Product Specifications

• Peptide Name: GHK-Cu
• Molecular Formula: C14H24CuN6O4
• Molecular Weight: ≈340.38 g/mol
• CAS Number: 49557-75-7 (GHK peptide); 89030-95-5 (GHK-Cu complex)
• Sequence: Gly-His-Lys (GHK) complexed with Cu²⁺
• Purity: ≥99% (HPLC verified)
• Form: Lyophilized powder
• Storage: -20°C (long-term) | 2–8°C (short-term) | Protect from light
• Shelf Life: Up to 12 months when stored sealed and dry

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Compound Overview

GHK-Cu is a copper-binding tripeptide complex composed of the amino acid sequence Gly-His-Lys coordinated with divalent copper (Cu²⁺). The presence of the copper ion forms a peptide–metal coordination complex that influences physicochemical stability, charge distribution, and analytical detection characteristics in laboratory workflows.

In laboratory research settings, GHK-Cu is evaluated for peptide–metal interaction characterization, structural stability profiling, and analytical quantification using chromatographic and mass spectrometry techniques. Experimental literature describes its classification within short regulatory peptide complexes studied in controlled in vitro and preclinical model systems. All data referenced on this page is derived from published preclinical animal and in vitro studies. No human clinical trials have established approved uses for GHK-Cu as a research compound.

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Published Preclinical Research

Published literature describes copper-binding tripeptide complexes such as GHK-Cu as defined research compounds investigated within controlled experimental systems.

• Peptide–metal coordination characterization and structural stability profiling
• Analytical identification using LC-MS and chromatographic methodologies
• Comparative evaluation of short peptide complexes in biological matrices
• In vitro modeling of peptide–metal interaction dynamics under controlled conditions

All data referenced on this page is derived from published preclinical animal and in vitro studies. No human clinical trials have established approved uses for GHK-Cu.

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Research Applications

• Peptide–metal complex identity confirmation using LC-MS workflows
• Method development for short peptide detection and quantification
• Structural characterization of coordination complexes
• Comparative analytical evaluation of regulatory peptide fragments
• Preclinical peptide stability research under validated laboratory protocols

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Physical Specifications

• Vial Size: 10 mL sterile vial
• Fill: 50mg or 100mg
• Appearance: White to off-white lyophilized powder
• Reconstitution Volume: Researcher-determined under validated laboratory protocols
• Post-Reconstitution Storage: 2–8°C, use within 30 days
• Solubility: Water-based laboratory solvents

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Compare to Related Compounds

KPV

• GHK-Cu is a tripeptide complexed with a copper ion, whereas KPV is a short linear tripeptide without metal coordination.
• These compounds differ in molecular composition, coordination chemistry, and analytical detection profiles under validated laboratory workflows.

LL-37

• GHK-Cu is a short copper-binding tripeptide complex, whereas LL-37 is a 37–amino acid linear antimicrobial peptide with a substantially larger sequence framework.
• Analytical differentiation is based on sequence length, molecular weight class, and the presence or absence of metal coordination.

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Handling & Storage

Lyophilized Stability:
When stored sealed in a dry environment protected from light, lyophilized peptide material may maintain chemical stability for up to 12 months at controlled room temperature. For maximum long-term preservation, storage at -20°C is recommended.

Post-Reconstitution Stability:
Following reconstitution under sterile laboratory conditions, the solution may maintain stability for up to 30 days when stored at 2–8°C. Minimize repeated freeze–thaw cycles and protect from light to preserve peptide integrity.

Handling:
Allow vial to equilibrate to room temperature before opening to prevent moisture condensation. Use sterile technique throughout preparation.

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Certificate of Analysis & Third-Party Testing

Every batch of BioEdge GHK-Cu undergoes independent third-party testing prior to release. Testing is performed by ISO-accredited laboratories with results available on each product page.

Identity Confirmation	Mass Spectrometry (MS)
Purity Assessment	High-Performance Liquid Chromatography (HPLC)
Minimum Purity Acceptance	≥99%
Heavy Metals	ICP-MS panel
Sterility	USP <71> Sterility Testing
COA Format	Batch-specific test results, downloadable on product page

To view testing results, scroll to the 3rd Party Testing section located below the product image.

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Why Researchers Choose BioEdge for GHK-Cu

Batch-specific COA from an independent lab. Not a generic PDF recycled across products. Every vial of GHK-Cu is backed by independent third-party laboratory testing, with a Certificate of Analysis available for review on our product page. HPLC confirms purity. Mass spectrometry confirms molecular identity. The COA corresponds to the specific batch you receive.

USA lyophilization. Many vendors import pre-filled vials from overseas and relabel them. BioEdge sources API and performs lyophilization within the United States, maintaining direct quality control over the final product.

No filler compounds. BioEdge GHK-Cu is pure lyophilized peptide. No mannitol, no bulking agents, no unnecessary excipients.

Same-day shipping. Domestic orders placed before 3pm ship the same day. Free shipping on orders over $150.

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Frequently Asked Questions

What is GHK-Cu?

GHK-Cu is a copper-binding tripeptide complex supplied exclusively for laboratory research use.

What is the CAS number for GHK-Cu?

49557-75-7 (GHK peptide); 89030-95-5 (GHK-Cu complex)

How should GHK-Cu be stored?

Store sealed in a dry environment protected from light. For maximum long-term preservation, storage at -20°C is recommended.

Is GHK-Cu third-party tested?

Yes. Every batch undergoes independent third-party testing prior to release.

Where can I access the COA for GHK-Cu?

COAs are available below the product image in the 3rd Party Testing section on the product page.

Is GHK-Cu FDA approved?

BioEdge GHK-Cu is sold strictly as a research compound for in vitro laboratory use. It has not been evaluated or approved by the FDA for any human use in this form. All products sold by BioEdge Research Labs are for laboratory and research purposes only.

Do you ship GHK-Cu within the USA?

Yes. BioEdge Research Labs is a USA based supplier with same day domestic shipping on orders placed before 3pm Eastern. Free shipping on orders over $150.

Can I get bulk pricing on GHK-Cu?

Yes. Contact BioEdge Research Labs directly for institutional and bulk research pricing.

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Published References

1. Pickart L, et al. “Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data.” International Journal of Molecular Sciences. 2018;19(7):1987. Link

2. Hu D, et al. “An injectable hydroxyapatite microsphere filler loaded with GHK-Cu tripeptide for anti-Inflammatory and antioxidant.” Colloids and Surfaces B: Biointerfaces. 2025;256(Part 1):114982. Link

3. Park J-R, et al. “The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice.” Oncotarget. 2016;7(36):58405-58417. Link

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RESEARCH USE ONLY Disclaimer

RESEARCH USE ONLY. GHK-Cu is sold exclusively for in vitro laboratory and research purposes. This product is not intended for human or animal consumption, clinical use, or therapeutic application. It has not been evaluated by the Food and Drug Administration (FDA) for safety, efficacy, or any medical purpose. Purchase and use of this product confirms the buyer will use it only in qualified research settings, in compliance with all applicable federal, state, and local regulations. BioEdge Research Labs is a chemical supplier, not a compounding pharmacy or clinical facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. BioEdge Research Labs makes no claims regarding therapeutic, diagnostic, or clinical applications of this compound.