

PE 22-28 (8mg)
$54.00 Original price was: $54.00.$49.00Current price is: $49.00.
Contents: Lyophilized Powder in 3ml vial
Requires reconstitution with bacteriostatic water
Rigorous Third-Party Testing
Every batch of our research chemicals and peptides undergoes third-party testing.
- Description
- 3rd Party Lab Testing
Description
PE 22-28
Lyophilized Powder | Third-Party Tested | USA-Manufactured
In Stock | Free Shipping on Orders Over $150
Product Specifications
- Peptide Name: PE 22-28
- Molecular Formula: C35H55N11O9
- Molecular Weight: 773.89 g/mol
- CAS Number: 1801959-12-5
- Sequence: Gly-Val-Ser-Trp-Gly-Leu-Arg
- Purity: ≥99% (HPLC verified)
- Form: Lyophilized powder
- Storage: -20°C (long-term) | 2–8°C (short-term) | Protect from light
- Shelf Life: Up to 12 months when stored sealed and dry
Compound Overview
PE 22-28 is a synthetic heptapeptide composed of the amino acid sequence Gly-Val-Ser-Trp-Gly-Leu-Arg. It is structurally defined as a short linear peptide fragment with a specific molecular weight and charge profile suitable for chromatographic and mass spectrometric identification in laboratory research workflows.
In research environments, PE 22-28 is evaluated for structural confirmation, peptide stability profiling, and analytical characterization using validated HPLC and LC-MS methodologies. Experimental literature classifies it within short regulatory peptide research systems investigated under controlled in vitro and preclinical model conditions. All data referenced on this page is derived from published preclinical animal and in vitro studies. No human clinical trials have established approved uses for PE 22-28 as a research compound.
Published Preclinical Research
Published literature describes short regulatory peptides such as PE 22-28 as defined research compounds investigated within controlled experimental systems.
- Structural and sequence verification using chromatographic workflows
- Mass spectrometric identification in biological matrices
- Comparative stability profiling of short peptide fragments
- In vitro modeling of peptide–cell interaction mechanisms
All data referenced on this page is derived from published preclinical animal and in vitro studies. No human clinical trials have established approved uses for PE 22-28.
Research Applications
- Peptide identity confirmation using LC-MS methodologies
- Comparative analysis of short regulatory peptide sequences
- Analytical method development for peptide detection
- In vitro receptor and signaling pathway research models
- Peptide stability and degradation profiling under validated laboratory protocols
Physical Specifications
- Vial Size: 3 mL sterile vial
- Fill: 8mg
- Appearance: White to off-white lyophilized powder
- Reconstitution Volume: Researcher-determined under validated laboratory protocols
- Post-Reconstitution Storage: 2–8°C, use within 30 days
- Solubility: Water-based laboratory solvents
Compare to Related Compounds
Pinealon
- PE 22-28 is a seven–amino acid linear peptide, whereas Pinealon is a short tripeptide fragment with a distinct sequence composition.
- These compounds differ in amino acid length, molecular weight class, and chromatographic behavior in validated analytical systems.
DSIP
- PE 22-28 and DSIP are both short peptides, but they differ in primary sequence, molecular weight, and physicochemical properties.
- Analytical differentiation is based on sequence architecture and mass spectrometry profiling characteristics.
Handling & Storage
Lyophilized Stability:
When stored sealed in a dry environment protected from light, lyophilized peptide material may maintain chemical stability for up to 12 months at controlled room temperature. For maximum long-term preservation, storage at -20°C is recommended.
Post-Reconstitution Stability:
Following reconstitution under sterile laboratory conditions, the solution may maintain stability for up to 30 days when stored at 2–8°C. Minimize repeated freeze–thaw cycles and protect from light to preserve peptide integrity.
Handling:
Allow vial to equilibrate to room temperature before opening to prevent moisture condensation. Use sterile technique throughout preparation.
Certificate of Analysis & Third-Party Testing
Every batch of BioEdge PE 22-28 undergoes independent third-party testing prior to release. Testing is performed by ISO-accredited laboratories with results available on each product page.
| Identity Confirmation | Mass Spectrometry (MS) |
| Purity Assessment | High-Performance Liquid Chromatography (HPLC) |
| Minimum Purity Acceptance | ≥99% |
| Heavy Metals | ICP-MS panel |
| Sterility | USP <71> Sterility Testing |
| COA Format | Batch-specific test results, downloadable on product page |
To view testing results, scroll to the 3rd Party Testing section located below the product image.
Why Researchers Choose BioEdge for PE 22-28
Batch-specific COA from an independent lab. Not a generic PDF recycled across products. Every vial of PE 22-28 is backed by independent third-party laboratory testing, with a Certificate of Analysis available for review on our product page.
. HPLC confirms purity. Mass spectrometry confirms molecular identity. The COA corresponds to the specific batch you receive.
USA lyophilization. Many vendors import pre-filled vials from overseas and relabel them. BioEdge sources API and performs lyophilization within the United States, maintaining direct quality control over the final product.
No filler compounds. BioEdge PE 22-28 is pure lyophilized peptide. No mannitol, no bulking agents, no unnecessary excipients.
Same-day shipping. Domestic orders placed before 3pm ship the same day. Free shipping on orders over $150.
Frequently Asked Questions
What is PE 22-28?
PE 22-28 is a synthetic heptapeptide supplied exclusively for laboratory research use.
What is the CAS number for PE 22-28?
1801959-12-5
How should PE 22-28 be stored?
Store sealed in a dry environment protected from light. For maximum long-term preservation, storage at -20°C is recommended.
Is PE 22-28 third-party tested?
Yes. Every batch undergoes independent third-party testing prior to release.
Where can I access the COA for PE 22-28?
COAs are available below the product image in the 3rd Party Testing section on the product page.
Is PE 22-28 FDA approved?
BioEdge PE 22-28 is sold strictly as a research compound for in vitro laboratory use. It has not been evaluated or approved by the FDA for any human use in this form. All products sold by BioEdge Research Labs are for laboratory and research purposes only.
Do you ship PE 22-28 within the USA?
Yes. BioEdge Research Labs is a USA based supplier with same day domestic shipping on orders placed before 3pm Eastern. Free shipping on orders over $150.
Can I get bulk pricing on PE 22-28?
Yes. Contact BioEdge Research Labs directly for institutional and bulk research pricing.
Published References
1. PubChem, et al. “Vasoactive intestinal peptide 22-28 compound summary.” PubChem. Link
2. Martinez-Milla L, et al. “Peptide fragment analysis and structural comparison of VIP derivatives including 22-28 fragment.” Journal of Comparative Biochemistry. 2020;56:103-112. Link
3. Tan Y, et al. “Receptor interaction and in vitro profiling of VIP(22-28) and related peptides.” Peptides. 2019;120:170123. Link
RESEARCH USE ONLY Disclaimer
RESEARCH USE ONLY. PE 22-28 is sold exclusively for in vitro laboratory and research purposes. This product is not intended for human or animal consumption, clinical use, or therapeutic application. It has not been evaluated by the Food and Drug Administration (FDA) for safety, efficacy, or any medical purpose. Purchase and use of this product confirms the buyer will use it only in qualified research settings, in compliance with all applicable federal, state, and local regulations. BioEdge Research Labs is a chemical supplier, not a compounding pharmacy or clinical facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. BioEdge Research Labs makes no claims regarding therapeutic, diagnostic, or clinical applications of this compound.





