Sleep Support Starter Bundle

Description

Product Overview

The Sleep Support Starter Stack pairs DSIP (Delta Sleep-Inducing Peptide) and NA Selank Amidate, two complementary neuropeptides studied for their combined potential in sleep regulation, stress adaptation, and neuroendocrine signaling.

DSIP has been examined for its influence on sleep cycles, hormonal balance, and brainwave stabilization, while NA Selank Amidate has been studied in connection with anxiety modulation, cognitive performance, and neurotransmitter regulation.

Together, these compounds provide a comprehensive research model for exploring GABAergic activity, cortisol and melatonin rhythms, emotional regulation, and cognitive recovery during rest and stress adaptation cycles.

---

Technical Specifications

DSIP (Delta Sleep-Inducing Peptide): 10mg lyophilized peptide vial

NA Selank Amidate: 10mg lyophilized peptide vial

Purity: >99% (HPLC-tested)

Form: Lyophilized powder

Storage: Stable at room temperature before reconstitution; refrigerate after reconstitution

---

Summary of Preclinical Research Findings

Sleep Regulation and Circadian Stability

DSIP has been studied for its role in maintaining deep (delta wave) sleep and synchronizing circadian rhythm stability. In combination with Selank Amidate—known to affect neuropeptide and GABA receptor systems—this pairing supports laboratory exploration of sleep quality, recovery, and neural rest-state function.

Stress Response and Anxiety Modulation

Research indicates DSIP may interact with hypothalamic and pituitary pathways to stabilize hormonal responses under stress. Selank Amidate complements these effects through anxiolytic and neurochemical modulation, particularly via GABAergic and neuropeptide Y signaling models.

Neuroendocrine and Hormonal Regulation

The two peptides together provide a model for examining melatonin, cortisol, and growth hormone balance, alongside neurotransmitter homeostasis involving serotonin and dopamine. These pathways have been central to studies on mood, adaptation, and cognitive recovery during sleep-deprivation or stress.

Cognitive Function and Neuroplasticity

Selank Amidate’s influence on memory, learning, and synaptic plasticity extends the application of this stack into studies of cognitive stability and brain health. When combined with DSIP’s homeostatic properties, the pair enables deeper investigation into neuroprotective and restorative mechanisms of the central nervous system.

Immunomodulatory and Metabolic Correlations

Both peptides have been explored for their roles in regulating inflammatory markers and lipid metabolism. This allows researchers to examine neuroimmune communication and metabolic signaling related to rest-state recovery and endocrine feedback.

---

Suggested Research Applications

• Sleep cycle and circadian rhythm regulation models

• Stress adaptation and anxiety behavior studies

• GABAergic and neuropeptide Y pathway analysis

• Cortisol, melatonin, and growth hormone feedback mapping

• Cognitive function and neuroplasticity evaluation

• Neuroimmune and metabolic correlation research

• Brainwave and rest-state electrophysiology studies

---

For Research Use Only

DSIP 10mg + NA Selank Amidate 10mg (Sleep Support Starter Stack) is supplied by BioEdge Research Labs exclusively for laboratory and in vitro research.

• Not for human or animal use

• Not for medical or diagnostic purposes

• Purchase confirms that the buyer is a qualified researcher, 18 years or older

• All research use must comply with local and institutional regulations

---

Summary of References

DSIP in Sleep and Neuroendocrine Research

• Schoenen, J., et al. (1987). DSIP and EEG delta wave activity during sleep. Sleep, 10(2), 173–186. https://pubmed.ncbi.nlm.nih.gov/3550726/

• Graf, M. V., et al. (1982). DSIP effects on sleep architecture and rest-state EEG patterns. Brain Research Bulletin, 9(1–6), 539–544. https://pubmed.ncbi.nlm.nih.gov/6895513/

• Bohus, B., et al. (1987). Delta Sleep-Inducing Peptide and central circadian control systems. Neuroscience Letters, 76(3), 277–282. https://pubmed.ncbi.nlm.nih.gov/3620931/

• Martynska, L., et al. (2006). DSIP regulates hypothalamic hormones and stress adaptation responses. Journal of Physiology and Pharmacology, 57(Suppl 8), 43–54. https://pubmed.ncbi.nlm.nih.gov/16539679/

• Pan, W., et al. (2003). DSIP and regulation of autonomic nervous system function during stress. Brain Research, 977(1), 26–34. https://pubmed.ncbi.nlm.nih.gov/12782416/

Selank Amidate in Anxiety, Cognition, and Neurochemical Research

• Dolotov, O. V., et al. (2008). Anxiolytic peptide Selank modulates gene expression in the hippocampus. Doklady Biochemistry and Biophysics, 419(1), 88–91. https://doi.org/10.1134/s0012496608040066

• Andreeva, L. A., et al. (2003). Behavioral effects of Selank in anxiety models. Neuroscience and Behavioral Physiology, 33(5), 529–534. https://doi.org/10.1023/a:1011373002885

• Myasoedov, N. F., et al. (2008). Selank enhances cognitive function in animal models of stress. Neuroscience and Behavioral Physiology, 38(3), 333–338. https://pubmed.ncbi.nlm.nih.gov/18577961/

• Lunin, S. M., et al. (2016). Selank’s effect on cytokine expression in inflammatory response models. Journal of Molecular Neuroscience, 58(3), 393–400. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757669/

• Yashin, A. A., et al. (2004). Tuftsin-related peptides in lipid and cholesterol regulation. Neuroscience and Behavioral Physiology, 34(6), 697–702. https://pubmed.ncbi.nlm.nih.gov/14969422/

 

BioEdge Research Labs
Precision. Purity. Performance.

At BioEdge, we are committed to providing research professionals with the highest quality peptides on the market. Every compound we supply is manufactured in a cGMP-certified facility, undergoes rigorous third-party testing, and is intended strictly for in vitro or laboratory research use only.