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Description

What is Cagrilintide?

Cagrilintide is a long-acting amylin analog studied for its role in weight loss, appetite regulation, and metabolic balance. It is structurally designed to mimic the activity of natural amylin, a hormone co-secreted with insulin, and has been shown in research settings to work synergistically with GLP-1 receptor agonists to influence satiety and caloric intake.

In laboratory models, Cagrilintide has been investigated for its impact on obesity, body weight control, blood sugar regulation, and fat metabolism. It has also shown promise in preclinical studies examining cardiovascular outcomes, gastric emptying, and the maintenance of metabolic homeostasis.

Due to its longer half-life and consistent receptor binding profile, Cagrilintide offers a valuable research model for exploring amylin-based peptide therapies in chronic weight management and cardiometabolic conditions.

Cagrilintide 5mg Product Specifications

Why Choose BioEdge Research Labs Cagrilintide?

• Research Grade Purity: Verified purity >99% by third-party HPLC analysis.

• Secure Packaging: Designed to maintain peptide stability and prevent degradation during shipment and storage.

• Rapid Fulfillment: Most orders ship within 24 hours after payment confirmation from our U.S.-based facility.

• Researcher Support: Expert customer service tailored to licensed research professionals.

Summary of Preclinical Research Findings

Appetite and Satiety Regulation

Cagrilintide has been studied in preclinical and clinical models for its ability to promote feelings of fullness and reduce calorie intake. Its activity at amylin receptors and complementarity with GLP-1 agonists make it a potent candidate for appetite-focused metabolic research.

Obesity and Weight Loss

Studies have shown that Cagrilintide contributes to sustained body weight reduction in both animal and human subjects. It has been evaluated as a monotherapy and in combination with GLP-1 receptor agonists in obesity research protocols.

Fat Metabolism and Energy Balance

Research suggests that Cagrilintide plays a role in regulating fat stores and energy expenditure. Investigations into brown fat activation and lipid oxidation pathways are ongoing.

Blood Sugar and Insulin Sensitivity

Preclinical studies have explored how amylin analogs like Cagrilintide may improve glycemic control by slowing gastric emptying and improving insulin response, making it a useful model for blood sugar and diabetes-related research.

Cardiometabolic Health

Cagrilintide has shown potential in supporting cardiovascular function and lowering metabolic risk factors. Its ability to influence body composition and lipid profiles is a growing area of interest in cardiometabolic research.

Suggested Areas of Research

• Appetite control and satiety signaling pathways

• Weight loss and obesity models

• Blood sugar regulation and insulin response

• Fat metabolism and energy balance

• Combination studies with GLP-1 receptor agonists

• Cardiovascular and metabolic health

Handling & Storage Guidelines

• Store lyophilized Cagrilintide in a cool, dry place

• Refrigerate after reconstitution

• Use sterile laboratory solvents

• Protect from light, heat, and moisture

For Research Use Only

Cagrilintide is supplied by BioEdge Research Labs exclusively for laboratory testing and in vitro research.

• Not for medical or diagnostic purposes

• Purchase confirms that the buyer is a qualified researcher, 18 years or older

• All usage must comply with local laws and lab safety guidelines

Summary of References

Cagrilintide in Obesity and Appetite Regulation

• Wilding, J. P. H., et al. (2021). Once-weekly Cagrilintide for weight management in people with overweight and obesity. The Lancet, 397(10288), 1736–1748. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01751-7/abstract

• Kaplan, L. M., et al. (2024). Cagrilintide: A Long-Acting Amylin Analog for the Treatment of Obesity. Cardiology in Review, 32(1), 14–22. https://journals.lww.com/cardiologyinreview/fulltext/2024/01000/cagrilintide__a_long_acting_amylin_analog_for_the.13.aspx

Cagrilintide and Amylin Receptor Binding

• Brodbeck, R. M., et al. (2021). Medicinal Chemistry of Long-Acting Amylin Analogs. Journal of Medicinal Chemistry, 64(18), 13743–13758. https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.1c00565

Blood Sugar Regulation and Insulin Sensitivity

• Martinez, R., et al. (2025). Cagrilintide influences postprandial glucose metabolism and energy intake in preclinical models. Molecular Metabolism Reports, 7, 100123. https://www.sciencedirect.com/science/article/pii/S2352396425002804

Cardiometabolic Research

• Johansen, L. M., et al. (2025). Dual action of amylin and GLP-1 agonists in metabolic regulation: A clinical perspective. Diabetes Therapy, 16(3), 557–570. https://link.springer.com/article/10.1007/s13300-025-01733-8

• Nguyen, H. T., et al. (2025). Amylin analogs reduce cardiovascular risk factors in experimental models. Nature Communications, 16, Article 58680. https://www.nature.com/articles/s41467-025-58680-y

BioEdge Research Labs
Precision. Purity. Performance.

At BioEdge, we are committed to providing research professionals with the highest quality peptides on the market. Every compound we supply is manufactured in a cGMP-certified facility, undergoes rigorous third-party testing, and is intended strictly for in vitro or laboratory research use only.