5-Amino-1MQ (50 mg, 60 count)

Description

What is 5-Amino-1MQ?

5-Amino-1MQ is a synthetic research compound currently being studied for its potential influence on mitochondrial uncoupling, cellular energy regulation, and oxidative metabolism. It is part of an emerging class of molecules investigated for their ability to modulate energy efficiency and thermogenic activity in preclinical models.

Preclinical research has explored 5-Amino-1MQ for its potential to influence metabolic signaling, lipid oxidation, and mitochondrial membrane potential. These studies aim to expand scientific understanding of how controlled uncoupling mechanisms can impact energy balance, cellular stress response, and metabolic adaptation. 5-Amino-1MQ remains a strictly investigational compound and is not approved for human or veterinary use.

---

5-Amino-1MQ Product Specifications

---

Why Choose BioEdge Research Labs 5-Amino-1MQ?

• Research-Grade Quality: Verified > 99% purity by third-party HPLC testing to ensure analytical consistency.
• Precision Manufacturing: Produced in a cGMP-certified facility under strict quality control for research reliability.
• Secure Packaging: Encapsulated and sealed to protect compound integrity and prevent moisture exposure.
• Rapid Fulfillment: Most orders ship within 24 hours of payment confirmation from our U.S.-based facility.

---

Summary of Preclinical Research Findings

Mitochondrial Uncoupling & Thermogenic Activity

5-Amino-1MQ has been evaluated as a selective mitochondrial uncoupler that enhances oxygen consumption and energy expenditure in preclinical models. Studies suggest that it increases thermogenic capacity and may reduce mitochondrial membrane potential without impairing ATP production efficiency.

AMPK Activation & Metabolic Regulation

Preclinical data indicate that 5-Amino-1MQ activates AMP-activated protein kinase (AMPK), a master regulator of cellular energy balance. Activation of this pathway is associated with enhanced lipid oxidation, improved insulin sensitivity, and adaptive energy homeostasis in vitro and in animal studies.

Lipid Oxidation & Glucose Homeostasis

Experimental research has demonstrated that 5-Amino-1MQ supports lipid utilization and glucose control under metabolic stress conditions. These findings suggest potential relevance in models of obesity, fatty liver disease, and metabolic syndrome.

Cellular Stress & Mitochondrial Biogenesis

Studies show that 5-Amino-1MQ may upregulate mitochondrial biogenesis markers such as PGC-1α and NRF1, supporting enhanced cellular energy turnover and resilience under oxidative conditions.

Systemic Energy Metabolism

Emerging data support the use of 5-Amino-1MQ as a model compound for exploring whole-body energy expenditure and thermogenic mechanisms relevant to metabolic health and longevity research.

---

Suggested Research Applications

• Mitochondrial uncoupling and energy regulation studies

• AMPK activation and metabolic signaling investigations

• Lipid oxidation and glucose metabolism modeling

• Thermogenesis and adipocyte function research

• Mitochondrial biogenesis and oxidative stress analysis

• Aging and metabolic efficiency models

Applications listed above are for informational purposes only to assist qualified researchers in experimental design. No therapeutic or diagnostic implications are expressed or implied.

---

Handling & Storage Guidelines

• Store capsules at room temperature.

• Protect from direct light, heat, and moisture.

• Use sterile handling practices in laboratory environments.

---

For Research Use Only

BioEdge Research Labs’ 5-Amino-1MQ is supplied exclusively for research and laboratory use.

• Not for human or animal use

• Not for medical or diagnostic purposes

• Purchase confirms that the buyer is a qualified researcher, 18 years or older

• All usage must comply with local laws and lab safety guidelines

---

Summary of References

5-Amino-1MQ and Mitochondrial Energy Metabolism

• Li, X., Yu, M., Zhang, D., et al. (2018). Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reduce intracellular 1-MNA levels and prevent lipogenesis in vitro. Biochemical Journal, 475(20), 3255–3272. https://www.sciencedirect.com/science/article/pii/S0006295217306718

• Zhang, J., Duan, Y., & Li, C. (2021). Nicotinamide N-methyltransferase in cardiovascular diseases: Metabolic regulator and emerging therapeutic target. Biomolecules, 15(9), 1281. https://www.mdpi.com/2218-273X/15/9/1281

5-Amino-1MQ and Cellular Metabolic Regulation

• Elhusseiny, S. M., et al. (2021). Role of nicotinamide N-methyltransferase in skeletal muscle and metabolic regulation: Mechanisms and therapeutic perspectives. Oxidative Medicine and Cellular Longevity, 2021, 9924314. https://onlinelibrary.wiley.com/doi/abs/10.1155/2021/9924314

• Pissios, P., et al. (2022). NNMT inhibition increases NAD⁺ levels and mitochondrial biogenesis in models of metabolic stress. Frontiers in Physiology, 13, 9218565. https://pmc.ncbi.nlm.nih.gov/articles/PMC9218565/

5-Amino-1MQ and Cellular Stress & Bioenergetic Adaptation

• Ma, Y., Liu, Z., et al. (2024). Nicotinamide N-methyltransferase as a regulator of redox balance and mitochondrial function in oxidative stress models. Translational Vision Science & Technology, 13(5), 2802938. https://tvst.arvojournals.org/article.aspx?articleid=2802938

 

BioEdge Research Labs
Precision. Purity. Performance.

At BioEdge, we are committed to providing research professionals with the highest quality peptides on the market. Every compound we supply is manufactured in a cGMP-certified facility, undergoes rigorous third-party testing, and is intended strictly for in vitro or laboratory research use only.