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MOTS-c (10mg)

Original price was: $65.00.Current price is: $59.00.

Contents: Lyophilized Powder in 3ml vial

Requires reconstitution with bacteriostatic water

Rigorous Third-Party Testing

Every batch of our research chemicals and peptides undergoes third-party testing.

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Description

MOTS-C

Lyophilized Powder | Third-Party Tested | USA-Manufactured

In Stock | Free Shipping on Orders Over $150


Product Specifications

  • Peptide Name: MOTS-C
  • Molecular Formula: C101H152N28O22S2
  • Molecular Weight: ≈2174.6 g/mol
  • CAS Number: 1627580-64-6
  • Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
  • Purity: ≥99% (HPLC verified)
  • Form: Lyophilized powder
  • Storage: -20°C (long-term) | 2–8°C (short-term) | Protect from light
  • Shelf Life: Up to 12 months when stored sealed and dry

Compound Overview

MOTS-C is a synthetic 16–amino acid peptide encoded within mitochondrial DNA and classified as a mitochondrial-derived peptide (MDP). Its linear amino acid sequence and defined molecular framework contribute to its physicochemical properties and analytical detectability in laboratory research workflows.

In laboratory research settings, MOTS-C is evaluated for peptide stability profiling, receptor and signaling interaction characterization, and analytical quantification using chromatographic and mass spectrometry methodologies. Experimental literature describes its classification within mitochondrial-derived regulatory peptide systems investigated in controlled in vitro and preclinical animal models. All data referenced on this page is derived from published preclinical animal and in vitro studies. No human clinical trials have established approved uses for MOTS-C as a research compound.


Published Preclinical Research

Published literature describes mitochondrial-derived peptides such as MOTS-C as defined research compounds investigated within controlled experimental systems.

  • Structural characterization and stability profiling in biological matrices
  • Analytical detection using LC-MS and chromatographic methodologies
  • In vitro modeling of mitochondrial-derived peptide signaling pathways
  • Comparative evaluation of regulatory peptide sequences in preclinical systems

All data referenced on this page is derived from published preclinical animal and in vitro studies. No human clinical trials have established approved uses for MOTS-C.


Research Applications

  • Peptide identity confirmation in laboratory analytical workflows
  • Mitochondrial-derived peptide signaling research models
  • Chromatographic method development for regulatory peptide detection
  • Mass spectrometry calibration and reference standard use
  • Preclinical peptide stability and degradation profiling

Physical Specifications

  • Vial Size: 3 mL sterile vial
  • Fill: 10mg
  • Appearance: White to off-white lyophilized powder
  • Reconstitution Volume: Researcher-determined under validated laboratory protocols
  • Post-Reconstitution Storage: 2–8°C, use within 30 days
  • Solubility: Water-based laboratory solvents

Compare to Related Compounds

NAD+

  • MOTS-C is a mitochondrial-derived regulatory peptide, whereas NAD+ is a metabolic coenzyme central to mitochondrial redox reactions and energy metabolism research.
  • These compounds differ structurally, with MOTS-C being a 16–amino acid peptide and NAD+ classified as a nucleotide-derived cofactor analyzed in biochemical pathway studies.

GHK-Cu

  • MOTS-C is a linear mitochondrial-derived peptide, whereas GHK-Cu is a tripeptide complexed with a copper ion forming a peptide–metal coordination complex.
  • Analytical differentiation is based on sequence length, molecular mass, and the presence or absence of metal coordination in laboratory characterization systems.

Handling & Storage

Lyophilized Stability:
When stored sealed in a dry environment protected from light, lyophilized peptide material may maintain chemical stability for up to 12 months at controlled room temperature. For maximum long-term preservation, storage at -20°C is recommended.

Post-Reconstitution Stability:
Following reconstitution under sterile laboratory conditions, the solution may maintain stability for up to 30 days when stored at 2–8°C. Minimize repeated freeze–thaw cycles and protect from light to preserve peptide integrity.

Handling:
Allow vial to equilibrate to room temperature before opening to prevent moisture condensation. Use sterile technique throughout preparation.


Certificate of Analysis & Third-Party Testing

Every batch of BioEdge MOTS-C undergoes independent third-party testing prior to release. Testing is performed by ISO-accredited laboratories with results available on each product page.

Identity Confirmation Mass Spectrometry (MS)
Purity Assessment High-Performance Liquid Chromatography (HPLC)
Minimum Purity Acceptance ≥99%
Heavy Metals ICP-MS panel
Sterility USP <71> Sterility Testing
COA Format Batch-specific test results, downloadable on product page

To view testing results, scroll to the 3rd Party Testing section located below the product image.


Why Researchers Choose BioEdge for MOTS-C

Batch-specific COA from an independent lab. Not a generic PDF recycled across products. Every vial of MOTS-C is backed by independent third-party laboratory testing, with a Certificate of Analysis available for review on our product page. HPLC confirms purity. Mass spectrometry confirms molecular identity. The COA corresponds to the specific batch you receive.

USA lyophilization. Many vendors import pre-filled vials from overseas and relabel them. BioEdge sources API and performs lyophilization within the United States, maintaining direct quality control over the final product.

No filler compounds. BioEdge MOTS-C is pure lyophilized peptide. No mannitol, no bulking agents, no unnecessary excipients.

Same-day shipping. Domestic orders placed before 3pm ship the same day. Free shipping on orders over $150.


Frequently Asked Questions

What is MOTS-C?

MOTS-C is a mitochondrial-derived peptide supplied exclusively for laboratory research use.

What is the CAS number for MOTS-C?

1627580-64-6

How should MOTS-C be stored?

Store sealed in a dry environment protected from light. For maximum long-term preservation, storage at -20°C is recommended.

Is MOTS-C third-party tested?

Yes. Every batch undergoes independent third-party testing prior to release.

Where can I access the COA for MOTS-C?

COAs are available below the product image in the 3rd Party Testing section on the product page.

Is MOTS-C FDA approved?

BioEdge MOTS-C is sold strictly as a research compound for in vitro laboratory use. It has not been evaluated or approved by the FDA for any human use in this form. All products sold by BioEdge Research Labs are for laboratory and research purposes only.

Do you ship MOTS-C within the USA?

Yes. BioEdge Research Labs is a USA based supplier with same day domestic shipping on orders placed before 3pm Eastern. Free shipping on orders over $150.

Can I get bulk pricing on MOTS-C?

Yes. Contact BioEdge Research Labs directly for institutional and bulk research pricing.


Published References

1. Lee C, et al. “The mitochondrial-derived peptide MOTS-C promotes metabolic homeostasis and reduces oxidative stress in cellular models.” Free Radical Biology & Medicine. 2016;98:24-34. Link

2. Zhang Y, et al. “MOTS-C regulation of metabolic and endocrine pathways in preclinical models.” Frontiers in Endocrinology. 2023;14:1120533. Link

3. Kim KH, et al. “Mitochondrial signaling peptide MOTS-C modulates cellular stress pathways and metabolic adaptation.” American Journal of Physiology-Endocrinology and Metabolism. 2020;319(5):E863-E874. Link


RESEARCH USE ONLY Disclaimer

RESEARCH USE ONLY. MOTS-C is sold exclusively for in vitro laboratory and research purposes. This product is not intended for human or animal consumption, clinical use, or therapeutic application. It has not been evaluated by the Food and Drug Administration (FDA) for safety, efficacy, or any medical purpose. Purchase and use of this product confirms the buyer will use it only in qualified research settings, in compliance with all applicable federal, state, and local regulations. BioEdge Research Labs is a chemical supplier, not a compounding pharmacy or clinical facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. BioEdge Research Labs makes no claims regarding therapeutic, diagnostic, or clinical applications of this compound.

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