MOTS-c (10mg)

Description

What is MOTS-c?

MOTS-c is a naturally occurring mitochondrial-derived peptide studied in laboratory research for its potential role in regulating metabolism, supporting energy production, and influencing cellular health. Composed of 16 amino acids, MOTS-c is encoded by mitochondrial DNA and has been shown in preclinical models to activate AMPK pathways, enhance glucose utilization, and support fat metabolism.

Researchers have investigated MOTS-c for its effects on weight regulation, exercise endurance, insulin sensitivity, and anti-aging mechanisms. Its activity has been linked to improved mitochondrial function, muscle performance, and metabolic flexibility in aging and diabetic animal models. MOTS-c continues to be a focus of metabolic and longevity-related studies in controlled in vitro settings.

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MOTS-c Product Specifications

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Why Choose BioEdge Research Labs MOTS-c?

• >99% Research-Grade Purity: Verified through independent HPLC testing

• Consistent Peptide Quality: Suitable for mitochondrial and metabolic studies

• Secure Laboratory Packaging: Ensures compound integrity in transit and storage

• Fast Shipping: Most orders ship within 24 hours after payment confirmation from our U.S.-based facility.

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Summary of Preclinical Research Findings

Weight Regulation and Fat Metabolism

• Studied for its ability to reduce fat accumulation and enhance energy use

• Linked to improved lipid metabolism and metabolic flexibility in obese models

• Applied in animal studies targeting adipose tissue remodeling and weight control

Glucose Control and Insulin Sensitivity

• Investigated for boosting glucose uptake via AMPK activation

• Associated with improved insulin response and blood sugar regulation

• Explored in diabetic models for metabolic rebalancing and glycemic support

Fatigue, Endurance, and Muscle Support

• Shown to increase physical capacity and muscle endurance in older subjects

• Used in studies on exercise performance, fatigue resistance, and mitochondrial energy output

• Applied in aging models examining muscle resilience and recovery

Anti-Aging and Longevity Research

• Evaluated for its role in promoting healthy aging at the cellular level

• Linked to mitochondrial homeostasis, nuclear gene signaling, and lifespan extension in animal models

• Studied in long-lived populations as a potential factor in metabolic resilience

Note: All findings above are derived from non-human, preclinical laboratory research. No claims are made regarding safety or efficacy in humans or animals.

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Suggested Areas of Research

• Metabolic regulation and fat loss models

• AMPK and mitochondrial energy signaling studies

• Insulin sensitivity and blood sugar control

• Anti-aging and longevity pathway investigations

• Fatigue, exercise performance, and endurance research

• Mitochondrial peptide signaling and nuclear gene crosstalk

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Handling & Storage Guidelines

• Store lyophilized MOTS-c peptide at room temperature in original vial

• Once reconstituted, refrigerate and use within an appropriate time frame

• Use only sterile, laboratory-grade solvents

• Avoid light, heat, and moisture to maintain compound stability

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For Research Use Only

MOTS-c from BioEdge Research Labs is provided strictly for scientific and laboratory research.

• Not for human or animal consumption

• Not for therapeutic, diagnostic, or clinical use

• Only available to qualified professionals age 18 or older

• All use must comply with applicable laws and institutional research guidelines

Disclaimer: This description is for educational and informational purposes only. No therapeutic claims are made or implied.

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Summary of References

MOTS-c in Weight Regulation and Fat Metabolism

• Kim, K. H., et al. (2019). MOTS-c peptide regulates adipose tissue metabolism and suppresses obesity in mice. Journal of Cellular Physiology, 234(11), 19263–19273. https://www.ncbi.nlm.nih.gov/pubmed/30725119

• Lee, C., et al. (2021). MOTS-c increases energy expenditure and improves metabolic flexibility. Nature Communications, 12, Article 6615. https://www.nature.com/articles/s41467-020-20790-0

MOTS-c in Glucose Control and Insulin Sensitivity

• Yadav, V., et al. (2023). MOTS-c improves glucose homeostasis and insulin signaling in diabetic models. Frontiers in Endocrinology, 14, 9905433. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905433/

• Kim, K. H., et al. (2016). MOTS-c mimics exercise effects on insulin sensitivity and glucose metabolism. Journal of Molecular Medicine, 94(4), 431–440. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116416/

MOTS-c in Energy, Fatigue, and Endurance Research

• Lu, H., et al. (2018). MOTS-c enhances physical capacity and muscle endurance in aging mice. Nature Communications, 9, Article 436. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185997/

• Reynolds, J. C., et al. (2019). Mitochondrial-derived peptide MOTS-c improves exercise performance and muscle metabolism. Aging Cell, 18(6), e13023. https://www.ncbi.nlm.nih.gov/pubmed/31293078

MOTS-c in Aging, Longevity, and Cellular Health

• Lee, C., et al. (2015). MOTS-c promotes metabolic homeostasis and healthy aging. Cell Metabolism, 21(3), 443–454. https://www.ncbi.nlm.nih.gov/pubmed/26476631

• Yadav, V., et al. (2023). MOTS-c links mitochondrial health to cellular aging pathways. Frontiers in Endocrinology, 14, 9905433. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905433/

• Reynolds, J. C., et al. (2015). The mitochondrial-derived peptide MOTS-c: A player in exceptional longevity. ResearchGate. https://www.researchgate.net/publication/281171907_The_mitochondrial-derived_peptide_MOTS-c_A_player_in_exceptional_longevity

• Cobb, L. J., et al. (2018). MOTS-c modulates nuclear gene expression to promote longevity-related outcomes. Aging (Albany NY), 10(3), 538–543. https://pubmed.ncbi.nlm.nih.gov/30468456/

 

BioEdge Research Labs
Precision. Purity. Performance.

At BioEdge, we are committed to providing research professionals with the highest quality peptides on the market. Every compound we supply is manufactured in a cGMP-certified facility, undergoes rigorous third-party testing, and is intended strictly for in vitro or laboratory research use only.