Kisspeptin (10mg)

Description

What is Kisspeptin?

Kisspeptin is a naturally occurring peptide studied for its essential role in reproductive hormone regulation and GnRH (gonadotropin-releasing hormone) signaling. It is a key player in activating the hypothalamic-pituitary-gonadal (HPG) axis, making it a primary focus in laboratory research involving puberty onset, fertility regulation, and endocrine balance.

Preclinical models have explored Kisspeptin for its ability to influence LH and FSH release, modulate sex hormone production, and regulate reproductive behavior. Its research applications extend to studies on hypothalamic activity, menstrual function, testicular signaling, and the broader landscape of hormonal rhythms.

---

Kisspeptin Product Specifications

---

Why Choose BioEdge Research Labs Kisspeptin?

Research Grade Purity: Verified purity >99% by third-party HPLC analysis.
Secure Packaging: Designed to maintain peptide stability and prevent degradation during shipment and storage.
Rapid Fulfillment: Most orders ship within 24 hours after payment confirmation.
Researcher Support: Expert customer service tailored to licensed research professionals.

---

Summary of Preclinical Research Findings

GnRH Activation and Hormone Signaling

Kisspeptin is known to directly stimulate GnRH secretion, initiating downstream release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This has made it a central subject in studies exploring puberty regulation, sex hormone balance, and ovarian and testicular function.

Fertility and Reproductive Health

Research has shown Kisspeptin’s involvement in reproductive cycle regulation, ovulation timing, and spermatogenesis. It is frequently studied in models of infertility, PCOS, and hypogonadotropic hypogonadism to understand hormone feedback mechanisms and potential therapeutic pathways.

Hypothalamic-Pituitary Axis and Sexual Maturation

Laboratory models have explored how Kisspeptin helps regulate neuroendocrine signaling through the hypothalamic-pituitary axis. Findings point to its influence on pubertal onset, sexual differentiation, and potential modulation of metabolic and behavioral cues linked to reproductive health.

---

Suggested Areas of Research

• GnRH and LH/FSH signaling pathways

• Reproductive hormone balance and feedback

• Puberty onset and sexual maturation

• Female cycle and ovulatory models

• Male fertility and testicular function

• Neuroendocrine regulation

• Hypothalamic-pituitary-gonadal axis studies

• PCOS, hypogonadism, and hormone disruption models

---

Handling & Storage Guidelines

• Store lyophilized peptide in a cool, dry place

• Refrigerate after reconstitution

• Use sterile laboratory solvents

• Protect from heat, light, and moisture

• Avoid repeated freeze-thaw cycles

---

For Research Use Only

Kisspeptin is supplied by BioEdge Research Labs exclusively for laboratory testing and in vitro research.

• Not for human or animal use

• Not for medical or diagnostic purposes

• Purchase confirms that the buyer is a qualified researcher, 18 years or older

• All usage must comply with local laws and lab safety guidelines

---

Summary of References

Kisspeptin in Reproductive Hormone Regulation

• Oakley, A. E. et al. (2009). Kisspeptin signaling in the brain and reproductive axis. Endocrine Reviews, 30(6), 713–743. https://academic.oup.com/edrv/article-pdf/30/6/713/10335003/edrv0713.pdf

• Seminara, S. B. et al. (2006). Kisspeptin-GPR54 signaling and puberty onset. Human Reproduction Update, 12(5), 631–639. https://academic.oup.com/humupd/article-pdf/12/5/631/2335738/dml023.pdf

• Pinilla, L. et al. (2012). The kisspeptin system and reproductive function. Endocrinology, 156(4), 1218–1229. https://academic.oup.com/endo/article-pdf/156/4/1218/8868879/endo1218.pdf

Kisspeptin in Fertility and Hypothalamic Signaling

• Jayasena, C. N. et al. (2014). Kisspeptin and reproductive hormone release in humans. Human Reproduction Update, 20(4), 485–500. https://academic.oup.com/humupd/article-pdf/20/4/485/9731468/dmu009.pdf

• Roa, J. et al. (2008). Hypothalamic control of reproduction through Kiss1 neurons. Human Reproduction Update, 15(2), 203–212. https://academic.oup.com/humupd/article-pdf/15/2/203/1746298/dmn058.pdf

• Clarke, I. J. (2010). Kisspeptin and GPR54: Critical gatekeepers of puberty. Physiology, 25(3), 171–181. https://journals.physiology.org/doi/pdf/10.1152/physiol.00009.2010

Kisspeptin in PCOS and Infertility Models

• Gutiérrez-Pascual, E. et al. (2015). Disrupted kisspeptin signaling in PCOS models. Endocrinology and Metabolism, 30(2), 124–132. https://synapse.koreamed.org/pdf/10.3803/enm.2015.30.2.124

• Millar, R. P. et al. (2015). Central and peripheral actions of kisspeptin in humans. NIHMS712569. https://pmc.ncbi.nlm.nih.gov/articles/PMC4587393/pdf/nihms712569.pdf

• Skorupskaite, K. et al. (2018). Kisspeptin’s role in human fertility regulation. Human Reproduction Update, 25(3), 326–344. https://academic.oup.com/humupd/article-pdf/25/3/326/28562032/dmy046.pdf

---

BioEdge Research Labs
Precision. Purity. Performance.

At BioEdge, we are committed to providing research professionals with the highest quality peptides on the market. Every compound we supply is manufactured in a cGMP-certified facility, undergoes rigorous third-party testing, and is intended strictly for in vitro or laboratory research use only.