Ipamorelin (10mg)

Description

What is Ipamorelin?

Ipamorelin is a synthetic pentapeptide classified as a selective growth hormone secretagogue (GHS). It is widely studied in in vitro and preclinical models for its interaction with the ghrelin receptor (GHS-R1a) and its potential to stimulate growth hormone (GH) release.

Ipamorelin is notable for its high specificity, demonstrating GH release without significantly affecting cortisol or prolactin levels in research models. This selective profile has made it a valuable tool in scientific studies exploring growth hormone regulation, endocrine signaling, and anabolic pathways under controlled laboratory conditions. Ipamorelin remains an investigational compound and is not approved for therapeutic use.

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Why Choose BioEdge Research Labs Ipamorelin?

• Research-grade purity verified at >99% through third-party testing.

• Sterile, tamper-resistant packaging designed for compound integrity.

• Most orders ship within 24 hours of payment confirmation from our U.S.-based facility.

• Dedicated customer support for researchers.

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Summary of Preclinical Research Observations

Growth Hormone Release

• Ipamorelin has been widely studied as a selective growth hormone secretagogue (GHS) for its ability to stimulate GH release through ghrelin receptor (GHS-R1a) activation in laboratory settings.

• Preclinical and human in vitro studies have shown that Ipamorelin promotes growth hormone secretion without significantly affecting cortisol or prolactin levels, distinguishing it from earlier peptides such as GHRP-6.

• This selectivity has been demonstrated in controlled endocrine models, supporting its use in research focused on pituitary regulation and peptide-induced GH signaling.

Ghrelin Receptor Activity and Signal Modulation

• Ipamorelin shows high binding affinity to GHS-R1a, a receptor involved in energy balance, neuroendocrine signaling, and GH pulsatility.

• Research has focused on understanding how synthetic ghrelin receptor agonists like Ipamorelin can selectively trigger downstream hormonal cascades while avoiding unwanted hormonal spikes.

• These findings contribute to in vitro models examining hypothalamic-pituitary signaling, appetite regulation, and neuroendocrine hormone pathways.

Muscle, Bone, and Tissue Regeneration

• Ipamorelin has been used in sarcopenia and musculoskeletal recovery models to examine GH-driven anabolic activity and tissue recovery potential.

• In animal and cell-based systems, growth hormone secretagogues like Ipamorelin have been shown to influence muscle regeneration, bone turnover, and protein synthesis, making it a compound of interest in orthopedic and metabolic research environments.

• Researchers have explored its use in the study of age-related muscle atrophy, GH modulation in bone density, and cellular repair processes.

Note: All findings described are from non-human, laboratory-based research. No claims are made regarding effects in humans or animals.

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Suggested Areas of Research for Ipamorelin

• Growth hormone signaling studies

• Ghrelin receptor pathway research

• Muscle and tissue regeneration protocols

• Endocrine axis modulation models

• In vitro peptide receptor binding assays

These applications are intended solely for licensed researchers designing experimental protocols. No therapeutic or diagnostic uses are implied or supported.

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Handling and Storage Guidelines

• Store lyophilized peptide at room temperature upon arrival

• Once reconstituted, refrigerate immediately

• Use sterile solvents appropriate for laboratory protocols

• Protect from light, moisture, and heat to preserve compound integrity

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For Research Use Only

BioEdge Research Labs’ Ipamorelin is provided exclusively for scientific laboratory research.

• Not for human or animal consumption

• Not for therapeutic, diagnostic, or clinical use

• Not for resale or application outside authorized research settings

By purchasing, you confirm you are a qualified professional and agree to comply with all local and institutional regulations. You must be 18 years or older to place an order. BioEdge Research Labs assumes no liability for misuse.

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Summary of References

Ipamorelin and Growth Hormone Release

• Thorner, M. O., Vance, M. L., Kaiser, D. L., & Jaffe, C. A. (1998). Growth hormone-releasing peptide-2 stimulates GH release in normal men and acts synergistically with GH-releasing hormone. Journal of Clinical Endocrinology & Metabolism, 83(2), 876–882. https://www.ncbi.nlm.nih.gov/pubmed/9849822

• Bowers, C. Y. (2001). Growth hormone-releasing peptides: Structure and kinetics. Hormone Research, 56(Suppl. 1), 38–43. https://www.ncbi.nlm.nih.gov/pubmed/11735244

Ghrelin Receptor Activation and Selectivity

• Chang, J. P., et al. (2016). GHSR1a signaling: Molecular determinants and role in growth hormone secretion and energy balance. Frontiers in Endocrinology, 7, 212. https://www.ncbi.nlm.nih.gov/pubmed/27186127

• Tolle, V., & Bluet-Pajot, M. T. (2019). Ghrelin receptor agonists: A new class of metabolic modulators. European Journal of Pharmacology, 860, 172568. https://www.sciencedirect.com/science/article/pii/S0223523418307347

Preclinical Studies in Muscle and Bone Research

• Elsaid, M., et al. (2018). Growth hormone secretagogues promote muscle regeneration in sarcopenia models. Journal of Cachexia, Sarcopenia and Muscle, 9(5), 918–926. https://pubmed.ncbi.nlm.nih.gov/30168238/

• Svensson, J., et al. (2016). Effects of GH secretagogues on bone turnover and bone mass: Preclinical and clinical findings. Current Osteoporosis Reports, 14(2), 85–93. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863553/

BioEdge Research Labs
Precision. Purity. Performance.

At BioEdge, we are committed to providing research professionals with the highest quality peptides on the market. Every compound we supply is manufactured in a cGMP-certified facility, undergoes rigorous third-party testing, and is intended strictly for in vitro or laboratory research use only.