GHK – CU

Description

What is GHK-Cu (Copper Peptide)?

GHK-Cu, short for glycyl-L-histidyl-L-lysine copper complex, is a naturally occurring copper-binding peptide that has been widely studied in preclinical models for its potential roles in tissue regeneration, skin remodeling, and wound healing. It is composed of the tripeptide GHK bound to a copper ion (Cu²⁺), which enhances its biological activity in cell signaling and repair mechanisms.

In laboratory settings, GHK-Cu has been investigated for its effects on collagen production, angiogenesis, anti-inflammatory responses, and hair follicle activity. It has also been explored in models related to oxidative stress modulation, skin elasticity, and extracellular matrix remodeling. Due to its involvement in a wide range of biological pathways, GHK-Cu continues to be a focus of research in cosmetic science, dermal healing, and cellular regeneration.

---

GHK-Cu Product Specifications

---

Why Choose BioEdge Research Labs GHK-Cu?

• Research-Grade Purity: >99% purity validated through independent HPLC testing.

• Stable Copper-Peptide Complex: Sourced for high consistency and structural reliability.

• Tamper-Resistant Packaging: Designed to maintain integrity during shipping.

• Fast Shipping: Most orders ship within 24 hours of payment confirmation from our U.S.-based facility.

---

Summary of Preclinical Research Findings

Skin Health and Wound Healing

• Studied for stimulation of collagen and glycosaminoglycan production

• Associated with improved wound closure rates in dermal tissue models

• Shown to support fibroblast activity and extracellular matrix remodeling

Hair Follicle and Dermal Regeneration

• Investigated in models examining follicle enlargement and hair growth signaling

• Applied in research involving scalp skin health and dermal papilla stimulation

• Linked to support of stem cell signaling in hair follicle regeneration

Anti-Inflammatory and Antioxidant Activity

• Observed to modulate inflammatory cytokines in tissue injury models

• Studied for its ability to bind free radicals and reduce oxidative stress markers

• Explored in skin aging models for its protective effects on dermal structure

Additional Areas of Study

• Used in cosmetic peptide research for firming, tightening, and elasticity testing

• Investigated in models of UV exposure and cellular damage

• Evaluated for angiogenic support and improved microvascular integrity

Note: All findings described above are derived from non-human, preclinical laboratory research. No statements are made regarding safety or efficacy in humans or animals.

---

Suggested Areas of Research

• Wound healing and tissue repair studies

• Hair follicle growth and regeneration models

• Collagen synthesis and anti-aging peptide assays

• Oxidative stress and free radical modulation

• Skin tightening and elasticity peptide protocols

• Cosmetic and dermatological research platforms

---

Handling & Storage Guidelines

• Store lyophilized GHK-Cu at room temperature in its original vial

• Once reconstituted, refrigerate immediately

• Use sterile laboratory-grade solvents

• Protect from moisture, light, and heat to preserve peptide stability

---

For Research Use Only

GHK-Cu from BioEdge Research Labs is distributed strictly for in vitro scientific and laboratory research.

• Not for human or veterinary use

• Not for diagnostic, therapeutic, or clinical application

• Purchase confirms the buyer is a qualified researcher age 18 or older

• All handling and use must comply with institutional and legal safety guidelines

Disclaimer: This content is provided for scientific and educational purposes only. No health or cosmetic claims are made or implied.

---

Summary of References

GHK-Cu in Wound Healing and Tissue Repair

• Pickart, L., & Margolina, A. (2018). Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data. International Journal of Molecular Sciences, 19(7), 1987. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/

• Pickart, L., & Margolina, A. (2018). GHK-Cu peptide induces a wound-healing phenotype in dermal fibroblasts via gene expression modulation. International Journal of Molecular Sciences, 19(7), 1987. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/

• Ahmed, U., et al. (2007). GHK-Cu and skin remodeling: Influence on wound contraction and extracellular matrix dynamics. Journal of Biomaterials Science, 18(8), 941–955. https://pubmed.ncbi.nlm.nih.gov/17703734/

GHK-Cu in Skin Regeneration and Cosmetic Research

• Wang, J., et al. (2020). GHK-Cu delivery via microneedles enhances skin regeneration in aging models. European Journal of Pharmaceutics and Biopharmaceutics, 156, 202–211. https://www.sciencedirect.com/science/article/pii/S0928493120335785

• Abedini, A., et al. (2015). Bioactive peptide-based nanomaterials for anti-aging and skin repair applications. BioMed Research International, 2015, Article ID 648108. https://www.hindawi.com/journals/bmri/2015/648108/

GHK-Cu in Hair Follicle and Cellular Activity

• Faghihi, G., et al. (2015). Effects of copper peptides on hair growth in mice: A pilot study. Iranian Red Crescent Medical Journal, 17(1), e25757. https://www.ncbi.nlm.nih.gov/pubmed/25745767

GHK-Cu in Anti-Inflammatory and Antioxidant Studies

• Abbas, M., et al. (2015). GHK-Cu as a modulator of oxidative stress in inflammation-driven skin models. Bioorganic & Medicinal Chemistry Letters, 25(24), 5590–5593. https://www.sciencedirect.com/science/article/pii/S0960894X14013262

• Mazurowska, L., & Mojski, M. (2017). GHK-Cu peptide shows antioxidant activity and protective effect against UV-induced oxidative damage. Acta Poloniae Pharmaceutica, 74(1), 255–260. https://www.ncbi.nlm.nih.gov/pubmed/28212278

 

BioEdge Research Labs
Precision. Purity. Performance.

At BioEdge, we are committed to providing research professionals with the highest quality peptides on the market. Every compound we supply is manufactured in a cGMP-certified facility, undergoes rigorous third-party testing, and is intended strictly for in vitro or laboratory research use only.