ARA-290 (16mg)

Description

What is ARA-290?

ARA-290 is a synthetic peptide engineered to target the innate repair receptor (IRR)—a component of the immune system involved in cell recovery and tissue repair. Unlike erythropoietin (EPO), from which it is derived, ARA-290 does not stimulate red blood cell production. Instead, it is studied in lab settings for its role in promoting nerve regeneration, reducing inflammation, and supporting organ function.

Preclinical research has explored ARA-290 in models of chronic pain, kidney injury, immune stress, and autoimmune-related tissue damage. Its potential to aid in wound healing, immune modulation, and metabolic recovery has made it a subject of growing interest in inflammation and nerve-related studies.

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ARA-290 Product Specifications

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Why Choose BioEdge Research Labs ARA-290?

Research Grade Purity: Verified purity >99% by third-party HPLC analysis.
Secure Packaging: Designed to maintain peptide stability and prevent degradation during shipment and storage.
Rapid Fulfillment: Most orders ship within 24 hours after payment confirmation.
Researcher Support: Expert customer service tailored to licensed research professionals.

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Summary of Preclinical Research Findings

Chronic Pain

ARA-290 has been studied extensively in chronic pain models, including those associated with diabetes, chemotherapy, and autoimmune conditions. It has been shown to reduce pain sensitivity, support nerve repair, and restore normal sensory function in controlled lab environments.

Kidney Function and Organ Protection

Research has explored ARA-290’s effects on kidney function, especially in settings involving inflammation-induced damage. In experimental models of ischemia and transplant injury, ARA-290 supported renal protection and reduced tissue stress.

Inflammation and Immune Modulation

ARA-290 interacts with the innate repair receptor, influencing the body’s natural anti-inflammatory pathways. Studies suggest it may reduce chronic inflammation while supporting cell recovery and tissue resilience.

Tissue Repair and Wound Healing

ARA-290 has demonstrated potential in improving wound healing and regenerative processes across multiple organ systems. In particular, it has shown protective effects in pancreas and eye models, and may help promote recovery from cytokine-induced injury.

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Suggested Areas of Research

• Chronic pain and sensory regulation

• Kidney function and transplant models

• Inflammation and immune modulation

• Wound healing and tissue regeneration

• Ischemia and organ stress response

• Autoimmune-related tissue injury

• Cytokine-induced cell damage

• Retinal and pancreatic protection

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Handling & Storage Guidelines

• Store lyophilized peptide in a cool, dry place

• Refrigerate after reconstitution

• Use sterile laboratory solvents

• Protect from heat, light, and moisture

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For Research Use Only

ARA-290 is supplied by BioEdge Research Labs exclusively for laboratory testing and in vitro research.

• Not for human or animal use

• Not for medical or diagnostic purposes

• Purchase confirms that the buyer is a qualified researcher, 18 years or older

• All usage must comply with local laws and lab safety guidelines

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Summary of References

ARA-290 in Chronic Pain and Nerve Repair

• Brines, M. et al. (2014). Nonerythropoietic EPO derivative improves symptoms of neuropathy. Molecular Medicine, 20(1), 27–36. https://link.springer.com/article/10.2119/molmed.2014.00215

• Davis, T. S. et al. (2014). ARA 290 in painful small fiber neuropathy: results of a randomized, placebo-controlled phase 2 study. Molecular Pain, 10, 13. https://journals.sagepub.com/doi/abs/10.1186/1744-8069-10-13

ARA-290 in Kidney Function and Transplant Injury

• Brines, M. et al. (2013). Activation of the innate repair receptor by ARA-290 improves renal function post-ischemia. Molecular Medicine, 19(1), 161–169. https://link.springer.com/article/10.2119/molmed.2013.00122

• Hoorn, E. J. et al. (2016). ARA-290 protects against delayed graft function. Transplantation, 100(3), 469–476. https://journals.lww.com/transplantjournal/fulltext/2016/03000/A_Nonhematopoietic_Erythropoietin_Analogue,_ARA.20.aspx

ARA-290 in Inflammation and Tissue Repair

• Heijink, M. et al. (2012). ARA-290 protects tissue from inflammation-induced damage in diabetes models. Molecular Medicine, 18(1), 228–235. https://link.springer.com/article/10.2119/molmed.2012.00332

• Liu, X. et al. (2022). ARA-290 supports pancreatic islet survival against cytokine stress. Academia.edu. https://www.academia.edu/download/104504562/an-engineered-innate-repair-receptor-agonist-ara-290-protects-ratislets-from-cytokineinduced-apoptosis-2155-6156-1000708.pdf

• Zhao, Y. et al. (2016). Innate repair signaling and metabolic outcomes. Metabolism, 65(3), 354–362. https://www.sciencedirect.com/science/article/pii/S0196978116300031

BioEdge Research Labs
Precision. Purity. Performance.

At BioEdge, we are committed to providing research professionals with the highest quality peptides on the market. Every compound we supply is manufactured in a cGMP-certified facility, undergoes rigorous third-party testing, and is intended strictly for in vitro or laboratory research use only.